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Both HA and PRP linked with significantly improved pain relief in patients with knee OA

HOME > Platelet Rich Plasma Therapy > Both HA and PRP linked with significantly improved pain relief in patients with knee OA
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  • June 29, 2017
  • Platelet Rich Plasma Therapy

A total of 111 patients with symptomatic unilateral knee OA received a series of either leukocyte-poor PRP or HA injections under ultrasound guidance. Clinical data were collected before treatment and at 4 time points across a 1-year period. Synovial fluid was also collected for analysis of proinflammatory and anti-inflammatory markers before treatment and at 12 and 24 weeks after treatment.

Significant improvements were seen in other patient-reported outcome measures, with results favoring PRP over HA. Preceding a significant difference in subjective outcomes favoring PRP, there was a trend toward a decrease in 2 proinflammatory cytokines, which suggest that the anti-inflammatory properties of PRP may contribute to an improvement of symptoms.
Read more.
ClinicalTrials.gov (Identifier: NCT02588872).
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